Pulmonary Tuberculosis (TB): Symptoms, Diagnosis, Treatment & Prevention


📌 What Is Pulmonary Tuberculosis?

Pulmonary tuberculosis (TB) is a contagious bacterial infection that mainly affects the lungs, caused by Mycobacterium tuberculosis. Despite advances in medicine, TB remains a major global health concern, particularly in developing countries. It spreads through the air when an infected person coughs, sneezes, or speaks.


🔍 How TB Spreads

Tuberculosis is transmitted aerosolically:

  • Inhalation of airborne droplets from a person with active TB.
  • Prolonged exposure increases the risk (e.g., living in the same house).
  • TB is not spread by touching, kissing, or sharing food.

⚠️ Signs and Symptoms of Pulmonary TB

Pulmonary TB often develops slowly. Early detection is key.

Common SymptomsAdvanced or Severe Symptoms
Persistent cough (>2–3 weeks)Coughing up blood (hemoptysis)
Chest pain or discomfortNight sweats
Fever (especially in the evening)Weight loss and fatigue
Shortness of breathLoss of appetite
Mild chillsWeakness and low-grade fever

🧪 Diagnosing Pulmonary Tuberculosis

A doctor may use a combination of the following:

🔬 Laboratory Tests

  • Sputum smear microscopy: detects acid-fast bacilli (AFB)
  • GeneXpert MTB/RIF test: rapid test for TB & rifampicin resistance
  • TB culture: most accurate but takes time

🩻 Imaging

  • Chest X-ray: shows lung lesions, cavities, or infiltrates

🩸 Other Tests

  • Tuberculin skin test (Mantoux test)
  • Interferon-Gamma Release Assays (IGRA)

💊 Treatment of Pulmonary TB

🔹 Standard Anti-TB Therapy (First-Line)

The initial phase (2 months):

  • Rifampicin (R)
  • Isoniazid (H)
  • Pyrazinamide (Z)
  • Ethambutol (E)

The continuation phase (4 months):

  • Rifampicin + Isoniazid

⏱️ Total Duration: At least 6 months

📌 It is critical to complete the full course to prevent drug resistance.


⚠️ Drug-Resistant TB (MDR-TB and XDR-TB)

  • MDR-TB: Resistant to at least rifampicin and isoniazid
  • XDR-TB: Resistant to multiple drugs, including fluoroquinolones

Treatment is longer (up to 18–24 months) and may include injectable drugs or newer oral drugs like bedaquiline.


🛡️ Prevention of Pulmonary Tuberculosis

✅ Key Preventive Measures:

  • Early diagnosis and treatment of active TB cases
  • BCG vaccine at birth (offers protection to children)
  • Isolation of infectious individuals
  • Proper ventilation in homes and public places
  • Wearing masks in high-risk settings

👥 Who’s at Risk?

  • Close contact with active TB patients
  • People with HIV/AIDS
  • Individuals with malnutrition or chronic illness
  • Healthcare workers
  • People living in overcrowded or poorly ventilated areas

👨‍⚕️ When to See a Doctor

Seek immediate care if:

  • You’ve had a cough for more than 2 weeks
  • You have weight loss, fever, or night sweats
  • You’ve been in close contact with a TB patient

✅ Final Thoughts

Pulmonary TB is preventable, treatable, and curable. Early detection and strict adherence to treatment can save lives and stop the spread. With rising cases of drug-resistant TB, it’s more important than ever to raise awareness and ensure timely diagnosis and management.

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